Drug detection

Responsible person: Elisabetta Chicca
This work is carried out in collaboration with the Integrated System Labratory, EPFL - École Polytechnique Fédérale de Lausanne, Switzerland

The treatment of serious diseases like cancer sometimes requires drastic measures. Unfortunately every human being reacts differently so that a therapy, while helping one person, could harm another. The concept of distributed diagnostics and personalized therapy aims to tackle that problem by developing individual solutions and observe the patients predisposition, metabolism and the efficiency of the treatment on a molecular level. But in the same way it require small and cost efficient devices, that are not reserved for big clinics, but for every day use.

Schematic overview of the steps required for drug detection with a neural network

In collaboration with the EPFL we are working on a promising approach with amperometric biosensing using cytochrome P450. While the EPFL is developing the sensor, we use a neural network approach to analyse the sensors data. Although this research is in an early state we are able to predict concentrations with acceptable tolerance. And we could prove that our method also works for non-linear interaction of multiple drugs.